AN INTEGRATED PRECIPITATION AND ION-EXCHANGE CHROMATOGRAPHY PROCESS FOR ANTIBODY MANUFACTURING: PROCESS DEVELOPMENT STRATEGY AND CONTINUOUS CHROMATOGRAPHY EXPLORATION

19.01.2018

Development of an fast, easy, and material-saving process development platform for an integrated antibody purification process.
Combination of high throughput experiments with empirical and mechanistic modeling.
Application of the methods for the purification of an industrial antibody feed.
Yield and purity competitive to Protein A capture chromatography.