WP6: Advanced analytical tools
Cutting-edge, continuous, disposable manufacturing requires state of the art analytics for process and product monitoring. WP6 aims to develop analytical techniques for in-line/at-line use to ensure that product quality attributes are monitored during continuous processing. Existing and emerging technologies such as microfluidic devices, fourier-transform infra-red spectroscopy, focused beam reflectance measurements and UV spectroscopy are being investigated for their ability to provide (as close as possible to) real time data on process-related impurities, high molecular weight variants and product content during DSP operations. WP6 is led by Sandoz GmbH.