Two interesting publications in the field of advanced analytical tools
Two interesting publications in the field of advanced analytical tools were published recently in Biotechnology and Bioengineering journal and in Journal of Chromatography A. Short description of both and links are available...
Advances in downstream processing of biologics – Spectroscopy: An emerging process analytical technology
A review article was published focusing on the new concept of spectroscopy as a PAT method for the purification of biologics. The review focuses on a comprehensive overview over the field and an introduction into multi-variate data analysis.
Real-Time Monitoring and Control of the Load Phase of a Protein A Capture Step
Within the nextBioPharmDSP project a new approach was developed to monitor the loading and breakthrough of a protein A column in real-time. The approach was further used for real-time control of a lab scale chromatography system. The method may help in the further advancement of continuous chromatographic capture steps.